Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors
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چکیده
منابع مشابه
Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors.
The most common primary tumors of the human brain are thought to be of glial cell origin. However, glial cell neoplasms cannot be fully classified by cellular morphology or with conventional markers for astrocytes, oligodendrocytes, or their progenitors. Recent insights into central nervous system tumorigenesis suggest that novel molecular markers might be found among factors that have roles in...
متن کاملGlial brain tumors.
suggest that brain tumors might result from occupation, dietary and other personal and residential exposures, but studies of cell phone use and power frequency electromagnetic fields have found little to support a causal connection with brain tumors; caveats remain though [8] . Previous studies have reported inconsistent results regarding the effect of anthropometric and lifestyle factors on th...
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BACKGROUND Improvements in brain tumor treatments have led to an increase in the number of young women with brain tumors who are now considering pregnancy. The aim of this study is to evaluate the influence of pregnancy on brain tumor biology. METHODS In this institutional review board-approved retrospective study, we searched the institution's database for patients with glial brain tumors wh...
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Preoligodendrocytes have been described in cultures and tissue prints of adult human white matter (Armstrong et al., 1992). To characterize further these precursors of human oligodendrocytes, we have investigated whether they express genes playing a critical role in oligodendrocyte development. In the intact human brain, platelet-derived growth factor receptor alpha (PDGF alpha R) and myelin tr...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2001
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.181340798